NS 608
Epigenetics (also BIOGD 608[6080])
Fall. 2 credits. Prerequisites: BIOGD 281 and BIOBM 330, 332, or 333 or NS 320. Letter grades only. P. Soloway.
Epigenetic effects refer to reversible alterations in chromatin structure that can stably and heritably influence gene expression. Changes include covalent modifications to DNA itself or to proteins bound to DNA as well as noncovalent remodeling of chromatin. Course examines selected epigenetic phenomena described in several eukaryotes, mechanisms regulating these effects, and their phenotypic consequences when normal regulation is lost. Reading materials are from current literature, and participation in class discussion is required.