NS 475
Mechanisms Underlying Mammalian Developmental Defects (also BIOAP 475[4750])
Spring. 3 credits. Prerequisites: BIOBM 330, 331–332 or 333 (may be taken concurrently). Offered alternate years. D. Noden and P. Stover.
Developmental defects are present in nearly 5 percent of humans. Drawing upon current research, this course explores the causes of birth defects, emphasizing the interplay between genetic and environmental factors in the regulation of developmental processes. Emphasis is on nutritional disruptors, teratogens, and regulatory gene networks that are well characterized through animal studies and are associated with morphological, physiological, reproductive, or behavioral abnormalities in humans.